Modifying Enzymes
Cayman Chemical Oleoyl-D-lysInsodIum salt 10mg
An inhibitor of GlyT2a; selectively inhibits GlyT2a (IC50 = 48.3 nM) over GlyT1b (IC50 = >3,000 nM) in Xenopus oocytes expressing the human transporters; reduces allodynia in a nerve ligation rat model of neuropathic pain at 30 mg/kg, i.p.
Medchemexpress LLC Gastric lipase protein, human | >95.0% | 10UG
Recombinant human gastric lipase expressed in HEK293 cells and supplied as a His-tagged solution for research use. The enzyme catalyzes hydrolysis of triacylglycerols and is suitable for enzymatic activity assays, biochemical characterization, and reagent validation. Provided as a 10 μg vial with >95% purity; store at -80°C and avoid repeated freeze-thaw cycles.
- Recombinant human enzyme expressed in mammalian (HEK293) cells.
- C-terminal 6xHis tag facilitates purification and detection.
- High purity (>95%) suitable for biochemical and activity assays.
- Complete amino acid sequence available for identity confirmation.
- Stable at -80°C; aliquot to minimize freeze-thaw cycles.
Amsbio LLC Heparinase II, from Recombinant Flavobacterium heparinum - Research Grade
Heparinase II from Recombinant Flavobacterium heparinum - Research Grade
Bioss KD-Validated Exo/Endonuclease
Exo/Endonuclease G Primary Antibody Unconjugated Public Immunogen Range 350-368/368 Host Species Rabbit Target Species Human Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
Cayman Chemical Monoacylglycerol Lipase Block
Peptide Sequence: human monoacylglycerol lipase blocking peptide amino acids 1-14 (MPEESSPRRTPQSI) · To be used in conjunction with Cayman’s Monoacylglycerol Lipase Polyclonal Antibody (Item No. 100035) to block protein-antibody complex formation during analysis for monoacylglycerol lipase.
Biotang Inc Alkaline Phosphatase Bovine Intestinal, Alkaline Phosphatase Bovine, Alkaline Phosphatase is Dimeric protein having a molecular weight of 140 kDa, Mg++ stimulates the catalysis.
Alkaline Phosphatase Bovine Intestinal, Alkaline Phosphatase Bovine, Alkaline Phosphatase is Dimeric protein having a molecular weight of 140 kDa, Mg++ stimulates the catalysis.
New England Biolabs, Inc. Endonuclease III (Nth) – 1000 units
Endonuclease III (Nth) protein from E. coli acts as both N-glycosylase and a AP-lyase. The N-glycosylase activity releases damaged pyrimidines from double-stranded DNA, generating a basic (AP site). The AP-lyase activity of the enzyme cleaves 3 to the AP site leaving a 5' phosphate and a 3' ring opened sugar. Some of the damaged bases recognized and removed by Endouclease III include urea, 5, 6 dihydroxythymine, thymine glycol, 5-hydroxy-5 methylhydanton, uracil glycol, 6-hydroxy-5, 6-dihdrothimine and methyltartronylurea.
ABclonal Technology T4 RNA Ligase 2, truncated KQ
T4 RNA Ligase 2, truncated KQ (T4 Rnl2tr R55K, K227Q), specifically catalyzes the ligation of a 5-adenylated DNA or RNA to the 3 OH end of an RNA molecule. This enzyme-mediated ligation does not require ATP but necessitates a pre-adenylated adapter. T4 RNA Ligase 2, truncated KQ, a double-point mutant of T4 RNA Ligase 2 with R55K and K227Q substitutions, significantly reduces the non-specific ligation of RNA (such as concatenation or self-circularization) compared to T4 RNA Ligase 2, truncated, while maintaining enzyme activity similar to that of T4 RNA Ligase 2, truncated.
New England Biolabs, Inc. Thymine-DNA Glycosylase (TDG)-500 units
Thymine-DNA glycosylase (TDG) catalyzes the hydrolysis of the N-glycosidic bond of thymine or uracil mispairs opposite guanine that arise from spontaneous deamination events of 5-methylcytosine (5mC) and cytosine, respectively.The excision of the mispaired thymine or uracil base leaves an abasic (AP) site that can then be chemically or enzymatically cleaved.
- Active on dsDNA
- Monofunctional glycosylase that removes dT or dU nucleobases mispaired with dG to create an AP site
- Removes 5-formylcytosine, 5-carboxylcytosine, 5-hydroxymethyluracil, ethenocytosine, 5-fluorouracilIsolated from a recombinant source
- Supplied with 10X TDG Reaction Buffer
Medchemexpress LLC HY-110115 10mg Medchemexpress, TC-Mps1-12 CAS:1206170-62-8 Purity:>98%
Medchemexpress, HY-110115 10mg TC-Mps1-12 CAS:1206170-62-8 TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical N-Oleoyl ProlIn 25mg
An endogenous N-acyl amine that is decreased in lumbar spinal cord after capsaicin administration (1 UG/10 µl) and has surfactant properties (critical micelle concentration = 4.8 µM)
Medchemexpress LLC TC-Mps1-12 | 1206170-62-8 | 99.8% | 324.38 | 100 MG
TC-Mps1-12 is a potent and selective monopolar spindle 1 (Mps1) inhibitor, with an IC50 of 6.4 nM. It inhibits the growth of pMps1 cell lines and A549 cells in a dose-dependent manner, exhibiting good pharmacokinetic properties.
- Potent and selective Mps1 inhibitor
- Inhibits the growth of pMps1 cell lines with IC50 values of 131 nM in autophosphorylation assay
- Inhibits the growth of A549 cells in a dose-dependent manner in vivo, showing 47% tumor growth inhibition at 100 mg/kg without body weight loss
- Exhibits good PK properties with a Cmax of 3542 ng/mL and AUC of 6604 ng h/mL at an oral dose of 25 mg/kg
ABclonal Technology Xanthine Oxidase (XDH) Rabbit mAb
Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
Biotang Inc Staphylokinase Recombinant, produced in E.Coli is a non-glycosylated polypeptide chain containing 136 amino acids and having a molecular weight of 15.5 kd.
Staphylokinase Recombinant, produced in E.Coli is a non-glycosylated polypeptide chain containing 136 amino acids and having a molecular weight of 15.5 kd.